Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture
January 1, 2023
ASA vs. LMWH prophylaxis after an extremity fracture requiring surgery or a pelvic fracture. ASA was non-inferior to LMWH, and death rates were equivalent; however, DVT rates were higher (2.5%) in the ASA group vs. the LMWH group (1.7%), while PE and bleeding rates were similar. I think ASA has a role for some patients in various high-risk settings.
